Recently Discovered Adipokines and Cardio-Metabolic Comorbidities in Childhood Obesity

Recently Discovered Adipokines and Cardio-Metabolic Comorbidities in Childhood Obesity

White adipose tissue (WAT) asset, in terms of cell number, fat storage capacity and endocrine function, is largely determined in early stages of life and is pivotal for shaping the WAT pro-inflammatory behavior. WAT derived adipokines have been shown to play a main role in several cardio-metabolic abnormalities of obesity. This review focuses on the most recently identified adipokines, namely a...

Psoriasis and Associated Cardio-metabolic Comorbidities

Comorbidities of Childhood Obesity

Metabolic Syndrome, Obesity and Vitamin D Deficiency Fundamental Metabolic Link Recently Discovered

The first article mentioning such a link has been published in May 2004 by the American Journal of Clinical Nutrition [1]. The study had enrolled 126 healthy, glucose-tolerant subjects and results have shown that 25-hydroxy-vitamin D levels were positively correlated with insulin sensitivity index, leading to the following conclusion: “Subjects with hypovitaminosis D are at higher risk of insul...

Obesity and Metabolic Comorbidities: Environmental Diseases?

Obesity and metabolic comorbidities represent increasing health problems. Endocrine disrupting compounds (EDCs) are exogenous agents that change endocrine function and cause adverse health effects. Most EDCs are synthetic chemicals; some are natural food components as phytoestrogens. People are exposed to complex mixtures of chemicals throughout their lives. EDCs impact hormone-dependent metabo...